An article in JAMA (June 6, 2012, Vol. 307, No. 21, page 2247) states, “For years, nonsteroidal anti-inflammatory drugs that target the…Cox-2 enzyme have been linked to increased cardiovascular risks. New research indicates that these elevated risks occur because COX-2 inhibitors suppress prostacyclin – a vasodilator and platelet inhibitor with heart protecting properties.”
This ‘new’ research has come much too late for the 50,000 who died and over 100,000 patients who suffered a stroke or a heart attack directly related to the use of a COX-2 inhibitor such as Vioxx or Celebrex.
However, simply looking at the mechanism of action of COX-2 inhibitors would lead anyone to predict that their use would be associated with an increased risk of cardiovascular problems including stroke and heart attack. Read more
50,000 People Die from Taking a Drug That Should Not Be Prescribed
David Brownstein, MD. says 50,000 people die from taking a drug that should not be prescribed.